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Abstract
FISH & Chips
Gene Expression in Single Cells
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Building on transcription data from microarrays, American researchers have created a three-dimensional, structural representation of gene expression in individual cells. The new technique, a combination of fluorescence in situ hybridization (FISH) and microchip technology, may also have applications as a medical diagnostic tool.
More Complications in the Amyloid Picture
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Long before amyloid protein fragments start to form the classic plaques associated with Alzheimer's disease (AD), they are wreaking havoc on a genetic level, Columbia University researchers reported today. A second team warned of A-beta's less notorious relative.
FISH & Chips: Gene Expression in Single Cells
Optical Mapping Approaches to Molecular Genomics - an abstract from an article appearing in Current Opinion in Biotechnology, 1997, 8:70-74.
Improved Procedure for Fluorescence in situ Hybridization on Tissue Microarrays - an MEDLINE abstract from an article appearing in Cytometry, 2001 Oct 45:83-6.
More Complications in the Amyloid Picture
A Multi-Talented Secreted Protein - an abstract from an article appearing in Trends in Neurosciences, 2001, 24:8:441-442.
Inducible and Constitutive Transcription Factors in the Mammalian Nervous System: Control of Gene Expression by Jun, Fos and Krox, and CREB/ATF proteins - an abstract from an article appearing in Cancer Res., 1999, Dec. 59:6042-5.
Disturbance of Neuronal Plasticity is a Critical Pathogenetic Event in Alzheimer's Disease - an abstract from an article appearing in International Journal of Developmental Neuroscience, 2001, 19:3:231 - 245.