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Causes of Leukemia: Bibliography of Journal Articles

The following articles are the result of links from listmembers and a search of the NCI PubMed site. Whenever possible, a link to the abstract or to the full text article is given.

2009

No Risk of Maternal EBV Infection for Childhood Leukemia. Rosamaria Tedeschi et al., Cancer Epidemiology, Biomarkers and Prevention, 09/18/09. Abstract.

Estrogen treatment induces MLL aberrations in human lymphoblastoid cells. Schnyder S et al., Leuk Res. 2009 Oct;33(10):1400-4. Epub 2009 Mar 5. PubMed abstract. "We conclude that concentrations of E2 and 4-OH-E2 that may occur during pregnancy, or during use of oral contraceptives, can cause aberrations of the MLL gene and could thus be a factor in the early events of leukemogenesis occurring in utero."

Fetal Growth and Risk of Childhood Acute Lymphoblastic Leukemia: Results From an Australian Case-Control Study. E. Milne et al., American Journal of Epidemiology Advance Access published online on May 28, 2009. Abstract. "Results of this study confirm earlier findings of a positive association between rapidity of fetal growth and subsequent risk of acute lymphoblastic leukemia in childhood, and they are consistent with a role for insulin-like growth factors in the causal pathway."

High hyperdiploid childhood acute lymphoblastic leukemia (review article). Kajsa Paulsson and Bertil Johansson, Genes, Chromosomes and Cancer, Published Online: 4 May 2009. Abstract. (Discusses etiology of high hyperdiploid ALL, with a general discussion of ALL etiology.)

The proportion of childhood leukaemia incidence in Great Britain that may be caused by natural background ionizing radiation. R Wakeford, G M Kendall and M P Little, Leukemia 23: 770-776; advance online publication, January 8, 2009. Abstract.

Childhood acute leukemia and residence next to gas stations and automotive repair garages: the ESCALE study (SFCE*). Pauline Brosselin et al., Occup Environ Med. Published Online First: 12 February 2009. Abstract.

Infectious proxies and childhood leukaemia: Findings from the United Kingdom Childhood Cancer Study (UKCCS). Eve Roman et al., Blood Cells, Molecules, and Diseases, Volume 42, Issue 2, March-April 2009, Pages 126-128. Abstract.

Allergies and childhood leukemia. Jeffrey S. Chang et al., Blood Cells, Molecules, and Diseases. Volume 42, Issue 2, March-April 2009, Pages 99-104. Abstract. "In this review, we provide an overview of recent findings from the Northern California Childhood Leukemia Study (NCCLS) on factors related to the immune system including child's vaccination history and measures of child's exposure to infectious agents, namely daycare attendance, infection during infancy, and parental social contact in the work place."

Infection and pediatric acute lymphoblastic leukemia. Xiaomei Ma et al., Blood Cells, Molecules, and Diseases, Volume 42, Issue 2, March-April 2009, Pages 117-120. Abstract.

The human major histocompatibility complex and childhood leukemia: An etiological hypothesis based on molecular mimicry. Malcolm Taylor et al., Blood Cells, Molecules, and Diseases, Volume 42, Issue 2, March-April 2009, Pages 129-135. Abstract. "Efforts are currently in progress to resolve these questions, using large leukemia case-control sample series such as the UK Childhood Cancer Study (UKCCS) and the Northern California Childhood Leukemia Study (NCCLS). Here we review the background to these studies, and present a novel hypothesis based on the paradigm of HLA-associated auto-immune disease that might explain an infection-based etiology of childhood leukemia."

Birth weight and childhood leukemia: A meta-analysis and review of the current evidence. International Journal of Cancer, Robert W. Caughey and Karin B. Michels, Published Online: 18 Dec 2008. Abstract. "The combined available evidence from observational studies suggests that high birth weight is associated with an increased risk of overall leukemia and ALL. For AML the risk may be elevated at both high and low extremes of birth weight. . . "

Cured meat, vegetables, and bean-curd foods in relation to childhood acute leukemia risk: A population based case-control study. Chen-yu Liu et al., BMC Cancer 2009, 9:15. Abstract. "Dietary exposure to cured /smoked meat and fish may be associated with leukemia risk through their contents of nitrites and nitrosamines among children and adolescents, and intake of vegetables and bean-curd foods may be protective."

2008

Etiology of common childhood acute lymphoblastic leukemia: the adrenal hypothesis. K Schmiegelow et al. Leukemia (2008) 22, 2137–2141. Abstract.

Infections in early life and childhood leukaemia risk: a UK case–control study of general practitioner records. C R Cardwell et al. British Journal of Cancer advance online publication 30 September 2008. Abstract. "Our study provides no support for the Greaves hypothesis, which proposes that reduced or delayed exposure to infections in early life increases the risk of childhood ALL."

Prenatal origin of childhood acute lymphoblastic leukemia, association with birth weight and hyperdiploidy. B Gruhn et al. Leukemia (2008) 22, 1692–1697. Abstract.

A population-based, case–control study of green tea consumption and leukemia risk in southwestern Taiwan. Yau-Chang Kuo et al. Abstract. Cancer Causes Control. 2008 Aug 28. [Epub ahead of print]

Etiology of common childhood acute lymphoblastic leukemia: the adrenal hypothesis. K Schmiegelow, T Vestergaard, S M Nielsen and H Hjalgrim. Leukemia advance online publication 21 August 2008. Abstract. More on early childhood infections and the incidence of leukemia.

Socioeconomic status and childhood acute lymphocytic leukemia incidence in São Paulo, Brazil. Karina Braga Ribeiro et al. International Journal of Cancer, Volume 123 Issue 8, Pages 1907-1912, 2008. Abstract. (". . . early exposure to childhood infections, which has been found to decrease the risk of ALL.")

Childhood Leukaemia Near Nuclear Installations. Joseph Mangano and Janette D. Sherman. Letter to the editor, European Journal of Cancer Care. Volume 17 Issue 4, Pages 416 - 418, 2008. Link. Full text of this letter (not generally available) is useful, as it provides useful tables and links validating increased incidence of childhood leukemia, especially near power plants.

What do epidemiologists mean by population mixing? Graham R. Law et al. Pediatr Blood Cancer 2008;51:155-160, 2008. Abstract.

Risk of Childhood Leukemia Associated with Vaccination, Infection, and Medication Use in Childhood. The Cross-Canada Childhood Leukemia Study. Amy C. MacArthur, Mary L. McBride, John J. Spinelli, Sharon Tamaro, Richard P. Gallagher and Gilles P. Theriault. American Journal of Epidemiology 2008 167(5):598-606. Abstract.

2007

Leukaemia in young children living in the vicinity of German nuclear power plant. Peter Kaatsch et al. International Journal of Cancer, Volume 122, Issue 4, Pages 721 - 726. Abstract.

Childhood leukaemia and infectious exposure: A report from the United Kingdom Childhood Cancer Study (UKCCS). J. Simpson, A. Smith, P. Ansell, E. Roman. European Journal of Cancer, Volume 43, Issue 16, Pages 2396-2403. Abstract.

Adenovirus DNA is detected at increased frequency in Guthrie cards from children who develop acute lymphoblastic leukaemia. Gustafsson, B., et al. Br J Cancer. 2007 Oct 8;97(7):992-4. PubMed Abstract.

Parental social contact in the work place and the risk of childhood acute lymphoblastic leukaemia. Chang, J.S., et al. Br J Cancer. 2007 Oct 9. PubMed Abstract.

Evidence of population mixing based on the geographical distribution of childhood leukemia in Ohio. Brenda R. Clark, Amy K. Ferketich, James L. Fisher, Frederick B. Ruymann, Randall E. Harris, John R. Wilkins III. Pediatric Blood & Cancer Volume 49, Issue 6, 2007, p. 797-902. Abstract.

Increasing incidence of childhood leukaemia: a controversy re-examined. Shah, A., et al. Br J Cancer. 2007 Aug 21. PubMed abstract. "We provide evidence of a gradual increase in the incidence of childhood leukaemia over the twentieth century from examination of trends in both incidence and mortality in England and Wales. We conclude that much of the recorded increase is likely to be real."

MDR1 Gene Variants, Indoor Insecticide Exposure, and the Risk of Childhood Acute Lymphoblastic Leukemia. Urayama, K.Y., et al. Cancer Epidemiology Biomarkers & Prevention 16, 1172-1177, June 1, 2007. Abstract.

Maternal alcohol and coffee drinking, parental smoking and childhood leukaemia: a French population-based case-control study. Menegaux, F., et al. Paediatr Perinat Epidemiol. 2007 Jul;21(4):293-9. PubMed abstract.

MDR1 Gene Variants, Indoor Insecticide Exposure, and the Risk of Childhood Acute Lymphoblastic Leukemia. Kevin Y. Urayama et al. Cancer Epidemiology Biomarkers & Prevention 16, 1172-1177, June 1, 2007. Abstract.

Residential mobility and risk of childhood acute lymphoblastic leukaemia: an ecological study. Adelman, A. S., et al. Br J Cancer. 2007 May 29. PubMed Abstract.

New germline mutations in the hypervariable minisatellite CEB1 in the parents of children with leukaemia -- British Journal of Cancer. B G Davies., et al. PubMed abstract. "Gardner and co-workers advanced the hypothesis that the Seascale leukaemia cluster could have been caused by new mutations in germ cells, induced by paternal preconceptional irradiation (PPI) exposure at the Sellafield nuclear installation."

Effects of maternal age and cohort of birth on incidence time trends of childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev 1 Feb 2007 16(2): p. 347. MM Maule, F Merletti, G Pastore, C Magnani, and L Richiardi. Abstract.

2006

Birth characteristics, maternal reproductive history, and the risk of infant leukemia: a report from the Children's Oncology Group. Logan G. Spector, et al. Cancer Epidemiol Biomarkers Prev. 2007 Jan;16(1):128-34. PubMed abstract.

Number of Siblings and the Risk of Lymphoma, Leukemia, and Myeloma by Histopathology. Andrea Altieri, Felipe Castro, Justo Lorenzo Bermejo and Kari Hemminki. Cancer Epidemiology Biomarkers & Prevention Vol. 15, 1281-1286, July 2006 American Association for Cancer Research. Abstract.

Population-mixing at the place of residence at the time of birth and incidence of childhood leukaemia in France. European Journal of Cancer, Volume 42, Issue 7 , May 2006, Pages 927-933. J. Rudanta, B. Baccaïnib, M. Riperta, A. Goubina, S. Belleca, D. Hémona and J. Clave. Abstract. "The findings are consistent with epidemic models and support the hypothesis of an infectious aetiology relating to population-mixing. Population density may be seen as an indicator of the opportunity of contacts between inhabitants and should therefore be taken into account when investigating an infectious hypothesis."

Birth weight, maternal weight and childhood leukaemia. C C McLaughlin, M S Baptiste, M J Schymura1,2, P C Nasca and M S Zdeb. British Journal of Cancer (2006) 94, 1738-1744. Abstract.

Magnetic field exposure and long-term survival among children with leukaemia. D E Foliart, B H Pollock, G Mezei, R Iriye, J M Silva, K L Ebi, L Kheifets, M P Link, and R Kavet. British Journal of Cancer (2006) 94, 161-164. Abstract.

2005

Agricultural pesticides and lymphoproliferative childhood cancer in California. Reynolds P, Von Behren J, Gunier R, Goldberg DE, Hertz A. Scand J Work Environ Health. 2005;31 Suppl 1:46-54; discussion 5-7. PubMed Abstract.

Maternal pregnancy loss, birth characteristics, and childhood leukemia (United States). Ma X, Metayer C, Does MB, Buffler PA. Cancer Causes Control. 2005 Nov;16(9):1075-83. Abstract.

Community Clusters of Childhood Leukemia and Lymphoma: Evidence of Infection? Clark W. Heath Jr. American Journal of Epidemiology Advance Access published online on September 21, 2005. Abstract.

Day care in infancy and risk of childhood acute lymphoblastic leukaemia: findings from UK case-control study. C Gilham, J Peto, J Simpson, E Roman, T O B Eden, M F Greaves, F E Alexander, for the UKCCS Investigators. BMJ, doi:10.1136/bmj.38428.521042.8F (published 22 April 2005) Abstract. Full text.

Urbanisation and incidence of acute lymphocytic leukaemia among United States children aged 0-4. British Journal of Cancer (2005) 92, 2084-2088. Published online 10 May 2005. A S Adelman, C C McLaughlin, X-C Wu, V W Chen and F D Groves.

Living near high-voltage power lines could cause leukaemia. Khabir Ahmad. Lancet Oncology, Volume 6, Issue 7 , July 2005, Page 450.

Molecular biomarkers for the study of childhood leukemia. Smith MT, McHale CM, Wiemels JL, Zhang L, Wiencke JK, Zheng S, Gunn L, Skibola CF, Ma X, Buffler PA. Abstract.

Associations between Three Types of Maternal Bacterial Infection and Risk of Leukemia in the Offspring. Matti Lehtinen, Helga M. Ögmundsdottir, Aini Bloigu, Timo Hakulinen, Elina Hemminki, Margret Gudnadottir, Anne Kjartansdottir, Jorma Paavonen, Eero Pukkala, Hrafn Tulinius, Tuula Lehtinen, and Pentti Koskela. American Journal of Epidemiology Advance Access published online on August 24, 2005. Abstract.

Ethnic Difference in Daycare Attendance, Early Infections, and Risk of Childhood Acute Lymphoblastic Leukemia. Xiaomei Ma, Patricia A. Buffler, Joseph L. Wiemels, Steve Selvin, Catherine Metayer, Mignon Loh, Monique B. Does and John K. Wiencke. Cancer Epidemiology Biomarkers & Prevention Vol. 14, 1928-1934, August 2005. Abstract.

Maternal Diet and Acute Lymphoblastic Leukemia in Young Children. Eleni Petridou1,2, Evangelos Ntouvelis1, Nick Dessypris1, Agapios Terzidis1, Dimitrios Trichopoulos1,2 and the Childhood Hematology-Oncology Group. Cancer Epidemiology Biomarkers & Prevention Vol. 14, 1935-1939, August 2005. Abstract.

2004

Posters from the leukemia causes conference 9/6/04 in London.

Maternal dietary risk factors in childhood acute lymphoblastic leukemia (United States). Jensen CD, Block G, Buffler P, Ma X, Selvin S, Month S. Cancer Causes Control. 2004 Aug;15(6):559-70. PubMed Abstract. NIEHS press release.

Leukemia clusters paper. Occasional paper No 1 of the Occasional Papers of the Royal Society of Edinburgh. (I have a copy of this paper.)

2003

Family history of autoimmune thyroid disease and childhood acute leukemia. Perillat-Menegaux F, Clavel J, Auclerc MF, Baruchel A, Leverger G, Nelken B, Philippe N, Sommelet D, Vilmer E, Hemon D. Cancer Epidemiol Biomarkers Prev. 2003 Jan;12(1):60-3. PubMed Abstract.

2002

Critical Windows of Exposure to Household Pesticides and Risk of Childhood Leukemia. Xiaomei Ma, Patricia A. Buffler, Robert B. Gunier, Gary Dahl,3 Martyn T. Smith, Kyndaron Reinier, and Peggy Reynolds, Environmental Health Perspectives, Vol. 110, No. 9, September 2002. Available online on the Environmental Health Perspectives web site. (I have a pdf copy of this paper.)

Parental medication use and risk of childhood acute lymphoblastic leukemia. Wen W, Shu XO, Potter JD, Severson RK, Buckley JD, Reaman GH, Robison LL. Cancer. 2002 Oct 15;95(8):1786-94. (I have a pdf of this paper.) PubMed abstract.

Presence of clone-specific markers at birth in children with acute lymphoblastic leukaemia. Hjalgrim LL, Madsen HO, Melbye M, Jorgensen P, Christiansen M, Andersen MT, Pallisgaard N, Hokland P, Clausen N, Ryder LP, Schmiegelow K, Hjalgrim H. Br J Cancer. 2002 Oct 21;87(9):994-9. PubMed abstract. I have a copy of this paper.

Preferential loss of maternal 9p alleles in childhood acute lymphoblastic leukemia. Morison IM, Ellis LM, Teague LR, Reeve AE. Blood. 2002 Jan 1;99(1):375-7. PubMed abstract. Online article in the New Zealand Herald: Leukaemia study points to pre-birth factors in disease.

2001

Infective cause of childhood leukaemia and wartime population mixing in Orkney and Shetland, UK L J Kinlen, A Balkwill, Lancet Volume 357, Number 9259 17 March 2001.

2000

The United Kingdom Childhood Cancer Study. Kinlen LJ. Br J Cancer 2000 Mar;82(5):999. PubMed.

Paternal military service and risk for childhood leukemia in offspring. Wen WQ, Shu XO, Steinbuch M, Severson RK, Reaman GH, Buckley JD, Robison LL. Am J Epidemiol 2000 Feb 1;151(3):231-40. PubMed abstract.

Incidence of childhood precursor B-cell acute lymphoblastic leukaemia in northwest England. Richard J Q McNally, Jillian M Birch, G Malcolm Taylor, Osborn B Eden. THE LANCET • Vol 356 • August 5, 2000. I have a pdf of this article. PubMed abstract.

1999

Viral Causes of Malignancy, from Cancer Control: Journal of the Moffitt Cancer Center. 1999 MedScape article. (JCV linked to ALL.)

Quantifying the effect of population mixing on childhood leukaemia risk: the Seascale cluster. Dickinson HO, Parker L. Br J Cancer 1999 Sep;81(1):144-51. PubMed abstract.

Are the children of fathers whose jobs involve contact with many people at an increased risk of leukaemia? Fear NT, Roman E, Reeves G, Pannett B. Occup Environ Med 1999 Jul;56(7):438-42. PubMed abstract.

Prenatal origin of acute lymphoblastic leukaemia in children. J L Wiemels, G Cazzaniga, M Daniotti, O B Eden, G M Addison, G Masera, V Saha, A Biondi, M F Greaves. Lancet Volume 354 Issue 9189 Page 1499 1999. I have the pdf of this article.

Exposure to power-frequency magnetic fields and the risk of childhood cancer. UK Childhood Cancer Study Investigators. Lancet Volume 354 Issue 9194 Page 1925 1999. I have a pdf of this article.

Building a network of research in children's environmental health. Dearry AD, Collman GW, Saint C, Fields N, Redd S. Environ Health Perspect 1999 Jun;107 Suppl 3:391. Pub Med Abstract. Full Text.

Infant vaccinations and risk of childhood acute lymphoblastic leukaemia in the USA. Groves FD, Gridley G, Wacholder S, Shu XO, Robison LL, Neglia JP, Linet MS. Br J Cancer 1999 Sep;81(1):175-8. PubMed abstract.

A quest for seasonality in presentation of leukaemia and non-Hodgkin's lymphoma. Douglas S, Cortina-Borja M, Cartwright R. Leuk Lymphoma 1999 Feb;32(5-6):523-32. PubMed abstract.

Preconceptional paternal exposure to pesticides and increased risk of childhood leukaemia. Infante-Rivard C, Sinnett D. Lancet 1999 Nov 20;354(9192):1819.

Infant vaccinations and risk of childhood acue lymphoblastic leukaemia in the USA. Groves FD, GridletyG, Wacholder S et al. British Journal of Cancer 1999;81(1): 175-178. "Many studies have looked at the risk of leukaemia following vaccination for the usual infections of childhood (polio, measles, mumps, rubella, diphtheria, tetanus, rubella), and most have reported a protective effect. A recent study from the united states has found no general effect either positive or negative, but suggests that the Hib vaccine may be protective."

The role of parvovirus B19 infection in childhood acute lymphoblastic leukemia. Heegaard ED, Jensen L, Hornsleth A, Schmiegelow K. Pediatr Hematol Oncol 1999 Jul-Aug;16(4):329-34. PubMed abstract.

Acute leukemias in children from the city of Kiev and Kiev region after the Chernobyl NPP catastrophe. Gluzman DF, Abramenko IV, Sklyarenko LM, Nadgornaya VA, Zavelevich MP, Bilous NI, Poludnenko LY. Pediatr Hematol Oncol 1999 Jul-Aug;16(4):355-60. PubMed abstract.

Higher risk for acute childhood lymphoblastic leukaemia in Swedish population centres 1973-94. Swedish Child Leukaemia Group. Hjalmars U, Gustafsson G. Br J Cancer 1999 Jan;79(1):30-3. PubMed abstract.

Association of childhood leukaemia with factors related to the immune system. Schuz J, Kaletsch U, Meinert R, Kaatsch P, Michaelis J. Br J Cancer 1999 May;80(3-4):585-90. PubMed abstract.

1998

Parental occupational exposures and risk of childhood cancer. Colt JS, Blair A. Environ Health Perspect 1998 Jun;106 Suppl 3:909-25. PubMed abstract.

1997

High-contact paternal occupations, infection and childhood leukaemia: five studies of unusual population-mixing of adults. Kinlen LJ. 1: Br J Cancer 1997;76(12):1539-45. PubMed abstract.

Residential Exposure to Magnetic Fields and Acute Lymphoblastic Leukemia in Children. Linet MS, Hatch EE, , Kleinerman RA. Et al. The New England Journal of Medicine July 3, 1997 Vol. 337 No.1. Oncolink review.

Cancer in the offspring of radiation workers: a record linkage study. Draper GJ, Little MP, Sorahan T, Kinlen LJ, Bunch KJ, Conquest AJ, Kendall GM, Kneale GW, Lancashire RJ, Muirhead CR, O'Connor CM, Vincent TJ. BMJ 1997 Nov 8;315(7117):1181-8. PubMed abstract. Full Text article.

Seasonality in the diagnosis of acute lymphocytic leukaemia. Badrinath P, Day NE, Stockton D. Br J Cancer 1997;75(11):1711-3. PubMed abstract.

1995

Childhood leukemia and rural population movements: Greece, Italy, and other countries. Kinlen LJ, Petridou E. Cancer Causes Control 1995 Sep;6(5):445-50. PubMed abstract.

Childhood leukaemia and non-Hodgkin's lymphoma near large rural construction sites, with a comparison with Sellafield nuclear site. Kinlen LJ, Dickson M, Stiller CA. BMJ 1995 Mar 25;310(6982):763-8. PubMed abstract. Full text.

1992

Is acute lymphoblastic leukemia in children virus-related? MacMahon B. Am J Epidemiol 1992 Oct 15;136(8):916-24. PubMed abstract.

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