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Cord Blood Transplant Links
|  | | Contents |  | 
 |  | | Journal Articles |  | 
-
Outcomes after Transplantation of Cord Blood or Bone Marrow from
Unrelated Donors in Adults with Leukemia, by Mary J. Laughlin,
et. al, page 2265 and Transplants of
Umbilical-Cord Blood or Bone Marrow from Unrelated Donors in Adults
with Acute Leukemia by Vanderson Rocha, et. al., page 2276
from the New England Journal of
Medicine, November 25, 2004. These two
articles compare the use of cord blood to bone marrow from unrelated
donors in adults. The conclusion is that cord blood appears to be
equivalent to bone marrow from unrelated donors.
-
Stem Cell Transplantation (Cord Blood
Transplants) by Nelson J. Chao, Stephen
G. Emerson and Kenneth I. Weinberg from Hematology ,
American Society of Hematology Education Program Book
, 2004. Many adults in need of a stem cell
transplant can not find a donor. Cord blood provides a
source of stem cells for many such patients. Cord blood
has been widely accepted for use in children, this
article describes its use in adults. It discusses new
developments in the use of cord blood as well as studies
looking at expansion of cord blood cells.
-
Cord-Blood Transplants from Unrelated Donors in Patients with
Hurler's Syndrome, from the New England Journal of Medicine, May
6, 2004, Vol 350, No. 19, page 1960, by Susan L. Staba, et. al. Cord Blood
transplants seem to cure Hurler's disease in 20 children who
recieved such transplants.
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Hematopoietic Engraftment and Survival in Adult Recipients of
Umbilical-Cord Blood from Unrelated Donors, from the New England Journal of Medicine,
June 14, 2001, Vol 344, No. 24, page 1815, by Mary J. Laughlin,
et. al. This study looked at cord blood transplants from unrelated
mismatched donors in 68 adults. The rates of GVHD (both acute and
chronic) were reasonable and neutrophil recovery was better in
grafts that had a higher number of nucleated cells before being
frozen.
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Graft-Versus-Host Disease in Children Who Have Received a Cord-Blood
or Bone Marrow Transplant from an HLA-Identical Sibling,
from the New England Journal of
Medicine June 22, 1999, Vol 342, No. 25, page 1846, by Vanderson
Rocha et al. (registration, which is free is required). This study
compared 113 children (under the age of 15) who underwent cord-blood
transplants from matched siblings with 2052 children who under went
bone marrow transplants from matched siblings donors. Recipients of
cord blood were less likely to have GVHD (both acute and chrnoic), but
engraftment took longer.
- Outcomes
among 562 Recipients of Placental-Blood Transplants from Unrelated
Donors, from the New England
Journal of Medicine November 26, 1998, Vol 339, No. 22, page
1565, by Pablo Rubinstein et al. (registration, which is free is
required). This article describes the experience with cord blood
transplants between August 24, 1992, and January 30, 1998, from cord
blood stored at the New York Blood Center. Also an encompanying
editorial The
Future of Placental-Blood Transplantation by Robertson
Parkman in the same edition. Followup Correspondence:
Cord-Blood Transplants from the April 22, 1999 issue, Vol. 340,
No. 16, page 1287.
- Waste and
Longing -- The Legal Status of Placental-Blood Banking from
the New England Journal of Medicine
May 13, 1999, Vol 340, No. 19, page 1521, by George J. Annas discusses
the legal and to some extent ethical issues surronding the use of cord
blood. This articles looks at privacy concerns and ownership of the
blood among other issues.
 |  | | News Reports and Articles |  | 
- Cord Blood Banking and Its Potential Clinical Applications Report by David Harris , Ph.D, Director of the Arizona Health Sciences Center Cord Blood Bank .
- Frequently Asked Questions about Cord Blood Transplants from the Cord Blood Registry (CBR) .
- Umbilical Cord Blood Transplant --University of Minnesota
- The Hope, and Hype, of Cord Blood, By Denise Grady, an article on private cord blood banks from the New York Times (free registration required), December 1, 1998.
- Surviving
Leukemia...One Man's Cord Blood Miracle . Steve Sprague was diagnosed
with CML in 1995 when he was 47 years old. In those pre-Gleevec
days, the standard chemo for leukemia failed after only 17 months
when Steve went into blast crisis. An only child and unable to find
a matched unrelated donor for transplant, he became one of the first
to participate in a clinical trial for end-stage adult CMLers using
matching stem cells obtained from umbilical cord blood (UCB) and
expanded ex vivo (in the lab). Now a 4+ year survivor, Steve
volunteers his time as a cord blood advocate and has published a
short story about his unique transplant experience. His tale may be
helpful to patients, care-givers and even prospective parents
interested in donating their infant's umbilical cord blood. To obtain
a complimentary copy or for more information about UCB, email your
request to spraguecml@AOL.COM. Please
include your postal mailing address.
 |  | | Registries and Organizations |
 | 
A Parent's
Guide To Cord Blood Banks created and maintained
by Fran Verter, the mother of a Shai who underwent a stem
cell transplant, contains the most comprehensive list of
public cord blood banks.
- cordbloodforum.org
is a non-commercial, non-political source of information
and an opportunity for communication among transplant
physicians, transplant coordinators, cord blood bankers,
and patients. The goal and primary mission is to serve
patients in need of a hematopoietic cell transplant, by
disseminating information about the availability and
effectiveness of cord blood transplants for children and
adults
-
National Marrow Donor Program (NMDP) Cord Blood
Program is part of the NMDP network and provides a
central registry that can be searched for cord blood
units. There are also listings of NMDP affiliated cord
blood banks as well as other cord blood banks in the
U.S. and Canada.
- The Sibling
Donor Cord Blood Program of the Children's Hospital Oakland
Research Institute is a national program designed to
provide cord blood processing and storage for families
with a child who might benefit from a cord blood
transplant and who are expecting another
child. Currently (as of January, 2005) there is be no
charge for the initial processing, collection, and
storage of cord blood units.
- Carolinas Cord Blood
Bank at Duke University Medical Center, Durham,
North Carolina.
- The Cord Blood Donor
Foundation San Bruno, California, exists to increase the
public supply of cord blood by building an ethnically balanced stem
cell bank, to provide educational awareness and to conduct further
research in the use of cord blood stem cells.
- The
Elie Katz Umbilical Cord Blood Program was established in 1996
and is part of the Community Blood
Services, Paramus, New Jersey. Cord blood is collected both for private use (for a fee) and
for public use from Hospitals in parts of New Jersey and part of the
New York City Metropolitan area.
- New York Cord Blood
Center.
This is the largest cord blood center in the USA. It is run by Dr.
Pablo Rubinstein and does storage and apharesis of stem cells as well.
NY blood Center: 1 (800) 933-BLOOD (2566) or 212-570-3210.
- Cord Blood
Laboratory of the Puget Sound Blood Center
collects, stores and distributes cord blood collected from from donor
mothers who deliver at Swedish Medical Center in Seattle, Washington,
and from Kapiolani Medical Center for Women and Children in Honolulu,
Hawaii.
-
The St. Louis Cord Blood Bank located at Cardinal Glennon
Children's Hospital/ Saint Louis
University collects and stores cord blood from hospitals in a 150
mile radius around St. Louis. Includes
answers to frequently asked questions (FAQ) on cord blood
donation.
- UCLA Umbilical
Cord Blood Bank, is one of three sites selected
by the National Institutes of Health to build a national
cord blood bank system.
 |  | | Private Cord Blood Storage Facilities
|  |
A Parent's
Guide To Cord Blood Banks created and maintained
by Fran Verter, the mother of a child who underwent a stem cell
transplant. This site is highly recommended
, it provides information on various techniques
for processing and storing cord blood, questions to ask
cord blood banks before using them, links to journal
articles, cord blood banks and more. This site is a
must read for anyone who is considering
privately banking cord blood. Families that already have
a child who has a transplantable disease can bank the cord
blood from other children with no charge at The Sibling Donor Cord Blood
Program of the Children's
Hospital Oakland Research Institute.
- Alpha Cord is a network of
cord blood banks in several states.
- California
Cryobank, Umbilical Cord Blood Stem Cell Services, Santa
Monica, California.
- Corcell Company
- The Cord Blood Registry (CBR)
headquartered in San Bruno, California, with storage and lab
facilities located in, Tucson, Arizona.
- Cord Partners is a cord blood bank located in Los Angeles, California.
- Cryobank for Oncologic and Reproductive Donors, Inc (CORD), Middletown, New York.
- Cryobanks International, Inc.
- Cryo-Cell, Clearwater,
Florida.
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CureSource, Charleston,
South Carolina.
- Lifebank Cryogenics Corp., Vancouver, Canada.
- Lifebank, Florham Park, New Jersey.
- Neocells Umbilical Cord Blood
Stem Cell Preservation.
- New England Cord Blood
Bank, Boston, Massachusetts.
- United States Cryobanks of Florida and United States Center for Cord Blood, Altamonte Springs, Florida.
- Viacord, Inc. Boston, Massachusetts.
- Umbilical Cord Blood Storage links from Yahoo!.
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